I think the angle of the plane of the table as it's shown here would make Twi look from more above. The Twi in this picture looks like she should be on a table with a less steep angle, as she looks like we're watching her more from her back, and not from above as much.
But she looks really cute though, I love her mane the most, especially how it makes an up turn on her back. Her anime-like muzzle looks looks very cute too
I think I like this even more than the other one. I really like the shaping of human-Twi's hand, the detail of her clothes and the peaceful look on her face (not frustrated either, so I guess she's been drawing well and just got tired). And pony-Twily is adorable. There's the well-shaped plot too (and a well-placed tail on her), but it's not the core thing for me, just one of the points. I like how her wings and her horn and her flowing hair look here. Nicely done indeed!